Breakout Ventures is a San Francisco-based venture capital firm founded in 2016 that backs scientist-entrepreneurs building companies at the intersection of technology, biology, chemistry, and materials. With over $230 million under management across three funds, the firm positions itself as the first institutional check for founders who are PhDs commercializing their own research or deep-domain operators who understand the science behind their company.
Breakout focuses on the convergence of AI and science across biotech, life sciences, materials science, neurotechnology, robotics, and developer infrastructure. The firm is particularly drawn to founders solving problems where the underlying science creates a durable competitive advantage.
Breakout announced the close of Fund III at $114 million in March 2026, its largest fund to date. The fund received support from returning LPs including Cortes Capital, S-Cubed Capital, The Kraft Group, Pinegrove Venture Partners, and an affiliate of LH Capital, while adding new limited partners including JIMCO (the global investment arm of the Jameel family) and Korea Omega Investment Corporation.
The fund brings total assets under management to more than $230 million across three vehicles and is actively deploying capital into seed-stage companies, with plans to invest in more than 20 companies.
United States
